Basic terms related to genetics and drug therapy. Concept Introduction: Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

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Answer 1

Question

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.

Conclusion

Pharmacogenomics and pharmacogenetics are the basic terminologies that relate to both genetics and drug therapy.

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Considering the kcals the patient is receiving from propofol and D51⁄2NS, what should be the rate (ml/hr) of the tube feeding you selected? 30 ml/hr 45 ml/hr 55 ml/hr 65 ml/hr

You are seeing a 68 year-old male patient admitted to the ICU. He is sedated on the ventilator with propofol at 20ml/hr, D51⁄2NS running at 75ml/hr. and a past medical history of DM2, obesity, CAD, HTN, and Pneumonia. Ht 172cm, Wt 72kg, Alb 2.3, VE=7.9 L/min, Tmax =38.4 C 4.1 What is the total kcal this patient is receiving before the initiation of TF (Hint: include propofol and D51⁄2 NS in calculation)? 306 kcal 528 kcal 678 kcal 834 kcal What is the estimated kcal goal for this patient? 1787 kcal 1847 kcal 1927 kcal 2317 kcal What is the estimated protein need for this patient? 45 – 50 g/day 86 – 108g/day 108 – 180g/day 144 – 188 g/day What type of tube feeding formula would you recommend for this patient? Standard 1.5 kcal/ml formula Glycemic control product, 1.0 kcal/ml Low residue, high protein, nutritionally balanced,1.2 kcal/ml High protein, calorie control product, 2.0 kcal/ml

You are seeing a 68 year-old male patient admitted to the ICU. He is sedated on the ventilator with propofol at 20ml/hr, D51⁄2NS running at 75ml/hr. and a past medical history of DM2, obesity, CAD, HTN, and Pneumonia. Ht 172cm, Wt 72kg, Alb 2.3, VE=7.9 L/min, Tmax =38.4 C 4.1 What is the total kcal this patient is receiving before the initiation of TF (Hint: include propofol and D51⁄2 NS in calculation)? 306 kcal 528 kcal 678 kcal 834 kcal Which estimated prediction equation will you recommend to calculate the kcal need for this patient? Penn State Equation (2003b): Mifflin(0.96)+ VE (31) + Tmax (167)-6212 MifflinStJeor =(10xW)+(6.25xHt)–(5xAge)+5 Harris-Benedict equation: kcal/day (male) = 66 +13.8 (W) + 5.0(H) – (6.8 x A) Ireton-Jones equations (1992)(ventilator-dependent): 1925 – 10 (A) + 5 (W) + 281 (S) + 292 (T) + 851 (B) What is the estimated kcal goal for this patient? 1787 kcal 1847 kcal 1927 kcal 2317 kcal What is the…

Answer 2

Question

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.

Conclusion

Pharmacogenomics and pharmacogenetics are the basic terminologies that relate to both genetics and drug therapy.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.

Conclusion

Pharmacogenomics and pharmacogenetics are the basic terminologies that relate to both genetics and drug therapy.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.

Conclusion

Pharmacogenomics and pharmacogenetics are the basic terminologies that relate to both genetics and drug therapy.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.

Conclusion

Pharmacogenomics and pharmacogenetics are the basic terminologies that relate to both genetics and drug therapy.

Answer 6

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.

Conclusion

Pharmacogenomics and pharmacogenetics are the basic terminologies that relate to both genetics and drug therapy.

Answer 7

Chapter 8, Problem 1O

Summary Introduction

To discuss:

Basic terms related to genetics and drug therapy.

Concept Introduction:

Genetics is the branch of biology that deals with the study of genes and genomes and gene-related diseases. The way to treat such genetic disorders by drugs or conventional gene therapy paves the way for a new branch of science called pharmacogenomics, and pharmacogenetics is an important field of modern therapeutics.

Answer 8

Expert Solution & Answer

Explanation of Solution

Genetics is the branch of biology that deals with gene, genome, and all its associated disease patterns. Genetic disorders like Thalassemia, Hemophilia, SCID, and neurofibromatosis etc. are treated using drugs in ancient and modern times. After the advent of gene therapy, the defective genes in the genome that gives rise to disease are altered and replaced by the normal gene.

Pharmacogenomics and pharmacogenetics are the common terms that relate both to genetics and drug therapy. Pharmacogenomics deals with the combined effect of the whole genome and its reaction toward a particular drug in the living system.

Pharmacogenetics deals with the unified response of a single variant gene and its reaction towards a particular drug in the living system.