EP BIOLOGY:SCIENCE F/LIFE...-MOD.ACCESS
6th Edition
ISBN: 9780134839530
Author: BELK
Publisher: PEARSON CO
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Chapter 8, Problem 1MTC
The science that you learned in this chapter has helped you better understand the real-world example used throughout this discussion. Draw a line from the statement on the left to the science that supports it on the right.
Answers to Got It?, Visualize This, Working with Data, Sounds Right, But Is It?, Show You Know, and Chapter Review questions can be found in the Answers section at the back of the book.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
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(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 8 Solutions
EP BIOLOGY:SCIENCE F/LIFE...-MOD.ACCESS
Ch. 8 - What is the relationship between genotype and...Ch. 8 - Add labels to the figure that follows, which...Ch. 8 - Prob. 3LTBCh. 8 - Prob. 4LTBCh. 8 - Prob. 5LTBCh. 8 - Scientists have recently developed a process by...Ch. 8 - What is the physical basis for the independent...Ch. 8 - Prob. 8LTBCh. 8 - Prob. 9LTBCh. 8 - Prob. 10LTB
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