Evolution
Evolution
4th Edition
ISBN: 9781605356051
Author: Douglas Futuyma, Mark Kirkpatrick
Publisher: SINAUER
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Chapter 7, Problem 4PDT
Summary Introduction

To determine: The ratios of polymorphic sites within a species and the difference between species for synonymous and nonsynonymous changes.

Introduction: The McDonald-Kreitman (MK) test is a statistical test based on the logic of the ratio of the number of sites that are different between two species and the number of sites that are polymorphic within one of those species. When a locus is evolving neutrally, this ratio is expected to be same for synonymous and nonsynonymous changes.

Summary Introduction

To determine: The way in which the locus is evolving based on the result.

Introduction: The McDonald-Kreitman (MK) test is a statistical test based on the logic of the ratio of the number of sites that are different between two species and the number of sites that are polymorphic within one of those species. When a locus is evolving neutrally, this ratio is expected to be same for synonymous and nonsynonymous changes.

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