Essential Cell Biology (Fourth Edition)
Essential Cell Biology (Fourth Edition)
4th Edition
ISBN: 9780815345251
Author: Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D. Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 7, Problem 17Q

A.

Summary Introduction

To determine: Whether insertion of a single nucleotide near the end of the coding sequence harms an organism.

Concept introduction: Mutations are variations in codons caused by changes in nucleotides at or near the coding sequence. Some variations do not have much effect, as the genetic code is degenerate. These are silent mutations. However, some mutations can have an effect on cellular functions due to altered protein synthesis.

B.

Summary Introduction

To determine: Whether removal of a single nucleotide near the beginning of the coding sequence harms an organism.

Concept introduction: Mutations are variations in codons caused by changes in nucleotides at or near the coding sequence. Some variations do not have much effect, as the genetic code is degenerate. These are silent mutations. However, some mutations can have an effect on cellular functions due to altered protein synthesis.

C.

Summary Introduction

To determine: Whether deletion of three consecutive nucleotides in the middle of the coding sequence harms an organism.

Concept introduction: Mutations are variations in codons caused by changes in nucleotides at or near the coding sequence. Some variations do not have much effect, as the genetic code is degenerate. These are silent mutations. However, some mutations can have an effect on cellular functions due to altered protein synthesis.

D.

Summary Introduction

To determine: Whether deletion of four consecutive nucleotides in the middle of the coding sequence harms an organism.

Concept introduction: Mutations are variations in codons caused by changes in nucleotides at or near the coding sequence. Some variations do not have much effect, as the genetic code is degenerate. These are silent mutations. However, some mutations can have an effect on cellular functions due to altered protein synthesis.

E.

Summary Introduction

To determine: Whether substitution of one nucleotide for another in the middle of the coding sequence harms an organism.

Concept introduction: Mutations are variations in codons caused by changes in nucleotides at or near the coding sequence. Some variations do not have much effect, as the genetic code is degenerate. These are silent mutations. However, some mutations can have an effect on cellular functions due to altered protein synthesis.

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