Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Chapter 7, Problem 12PIAT
MODEL The distribution of melanosomes in cells is tightly regulated in animals that rapidly change color. Dark-colored cells have melanosomes scattered throughout the cytoplasm while light-colored cells have them aggregated near the nucleus. Draw a model of a cell representing each state, and predict how cells could use microtubules and motor proteins to change the distribution of melanosomes.
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The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.
The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the
pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin.
You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?
What protein is necessary for packaging acetylcholine into synaptic vesicles?
Chapter 7 Solutions
Biological Science (6th Edition)
Ch. 7 - What are three attributes of mitochondria and...Ch. 7 - PROCESS OF SCIENCE Which of the following results...Ch. 7 - Molecular zip codes direct molecules to particular...Ch. 7 - How does the hydrolysis of ATP result in the...Ch. 7 - Prob. 5TYUCh. 7 - Prob. 6TYUCh. 7 - 7. Most of the proteins that enter the nucleus...Ch. 7 - Prob. 8TYUCh. 7 - Prob. 9TYPSSCh. 7 - George Palade's research group used the...
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- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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