Nester's Microbiology: A Human Perspective
Nester's Microbiology: A Human Perspective
8th Edition
ISBN: 9780073522593
Author: Denise G. Anderson Lecturer, Sarah Salm, Deborah Allen
Publisher: McGraw-Hill Education
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Chapter 7, Problem 10SA
Summary Introduction

To review:

The reason for difficulties encountered in locating protein-coding regions in a genomic sequence.

Introduction:

The amino acids are building blocks of proteins. Protein encoding is initiated when a stretch of DNA (deoxyribonucleic acid) encodes genetic information for the amino acid sequence specific for the future protein. This is followed by the transcription process, in which this genetic information is transferred to mRNA (messenger ribonucleic acid) from any of the two strands of DNA. Once mRNA is formed, it undergoes processing steps like splicing, tailing, capping. This removes introns or non-coding sequences. Ultimately, the final step is protein synthesis from coding sequences of genome called translation occurs. Locating anonymous protein-coding regions in a genomic sequence can lead to ambiguity.

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