Brock Biology of Microorganisms (14th Edition)
Brock Biology of Microorganisms (14th Edition)
14th Edition
ISBN: 9780321897398
Author: Michael T. Madigan, John M. Martinko, Kelly S. Bender, Daniel H. Buckley, David A. Stahl, Thomas Brock
Publisher: PEARSON
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Chapter 6.7, Problem 2MQ
Summary Introduction

The small and solid support to which most genes are arranged and fixed spatially in a well-known pattern are generally called as gene chips. The microarrays estimate the RNA or DNA that hybridize to the sequence of DNA on the chip. When the denature of DNA occurs, the single strands of DNA can form double stranded hybrid molecules with other molecules of nucleic acid by almost or complementary base pairing. This process is called as hybridization or nucleic acid hybridization.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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