Human Biology
16th Edition
ISBN: 9781260482799
Author: Mader, Sylvia
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 6.5, Problem 2BTH
Are there other risk factors you think should be considered that would exclude individuals from donating blood?
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 6 Solutions
Human Biology
Ch. 6.1 - List the functions of blood in the human body.Ch. 6.1 - Prob. 2LOCh. 6.1 - Describe the composition of plasma.Ch. 6.1 - Summarize the components of blood.Ch. 6.1 - Prob. 2CYPCh. 6.1 - List the types of plasma proteins and explain why...Ch. 6.2 - Prob. 1LOCh. 6.2 - Prob. 2LOCh. 6.2 - Prob. 3LOCh. 6.2 - Prob. 1CYP
Ch. 6.2 - Prob. 2CYPCh. 6.2 - Prob. 3CYPCh. 6.3 - Prob. 1LOCh. 6.3 - Prob. 2LOCh. 6.3 - Prob. 3LOCh. 6.3 - Prob. 1CYPCh. 6.3 - Prob. 2CYPCh. 6.3 - Prob. 3CYPCh. 6.4 - Prob. 1LOCh. 6.4 - Prob. 2LOCh. 6.4 - Describe disorders associated with blood clotting.Ch. 6.4 - If you were a medical researcher, what other areas...Ch. 6.4 - Prob. 2BTHCh. 6.4 - Prob. 1CYPCh. 6.4 - Prob. 2CYPCh. 6.4 - Summarize a few of the blood-clotting disorders.Ch. 6.5 - Prob. 1LOCh. 6.5 - Prob. 2LOCh. 6.5 - 3.Summarize the role of Rh factor in hemolytic...Ch. 6.5 - Prob. 1BTHCh. 6.5 - Are there other risk factors you think should be...Ch. 6.5 - Prob. 1CYPCh. 6.5 - Prob. 2CYPCh. 6.5 - Prob. 3CYPCh. 6.6 - Summarize how the cardiovascular system interacts...Ch. 6.6 - Prob. 1CYPCh. 6 - Prob. 1ACh. 6 - Prob. 2ACh. 6 - Prob. 3ACh. 6 - Prob. 4ACh. 6 - Prob. 5ACh. 6 - Prob. 6ACh. 6 - Key:
a. lymphocytes
b. monocyte
c. neutrophils
d....Ch. 6 - Prob. 8ACh. 6 - Prob. 9ACh. 6 - Prob. 10ACh. 6 - Prob. 11ACh. 6 - Prob. 12ACh. 6 - Prob. 13ACh. 6 - Prob. 14ACh. 6 - Prob. 15ACh. 6 - Prob. 16ACh. 6 - Prob. 1TCCh. 6 - Prob. 2TCCh. 6 - Prob. 3TCCh. 6 - Prob. 4TCCh. 6 - Athletes who abuse erythropoietin have many more...Ch. 6 - Prob. 6TC
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