PRIN. OF LIFE (LL)-W/ACHIEVE
3rd Edition
ISBN: 9781319492069
Author: HILLIS
Publisher: MAC HIGHER
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Chapter 6.1, Problem 1LO
Summary Introduction
To describe: The events that occur in each of the three stages of cell-cell signaling.
Introduction: Cell signaling is the process of cell communication within the body. It is the ability of cells that perceive and respond to the micro-environment in the basis of tissue repair, immunity, and development. It is classified into five types, namely intracrine, autocrine, juxtacrine, paracrine, and endocrine.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
MAKE SURE ANSWERS HAVE UNITS if appropriate.
SHOW ALL WORK, including equation used, variables used and each step to your solution.
Chapter 6 Solutions
PRIN. OF LIFE (LL)-W/ACHIEVE
Ch. 6.1 - Prob. 1LOCh. 6.1 - Prob. 2LOCh. 6.1 - Prob. 3LOCh. 6.1 - Prob. 1RACh. 6.1 - Prob. 2RACh. 6.1 - Prob. 3RACh. 6.1 - Prob. 4RACh. 6.2 - Prob. 1LOCh. 6.2 - Prob. 2LOCh. 6.2 - Prob. 1FQ
Ch. 6.2 - Prob. 1RACh. 6.2 - Prob. 2RACh. 6.2 - Prob. 3RACh. 6.3 - Prob. 1LOCh. 6.3 - Prob. 2LOCh. 6.3 - Prob. 3LOCh. 6.3 - Prob. 1TKCh. 6.3 - Prob. 2TKCh. 6.3 - Prob. 3TKCh. 6.3 - Prob. 1FQCh. 6.3 - Prob. 1ICh. 6.3 - Prob. 2ICh. 6.3 - Prob. 3ICh. 6.3 - Prob. 4ICh. 6.3 - Prob. 5ICh. 6.3 - Prob. 1RACh. 6.3 - Prob. 2RACh. 6.3 - Prob. 3RACh. 6.4 - Prob. 1LOCh. 6.4 - Prob. 2LOCh. 6.4 - Prob. 3LOCh. 6.4 - Prob. 4LOCh. 6.4 - Prob. 1FQCh. 6.4 - Prob. 1RACh. 6.4 - Prob. 2RACh. 6.4 - Prob. 3RACh. 6 - Prob. 1.1QCh. 6 - Prob. 1.2QCh. 6 - Prob. 1.3QCh. 6 - Prob. 2.1QCh. 6 - Prob. 2.2QCh. 6 - Prob. 2.3QCh. 6 - Prob. 3.1QCh. 6 - Prob. 3.2QCh. 6 - Prob. 3.3QCh. 6 - Prob. 4.1QCh. 6 - Prob. 4.2QCh. 6 - Prob. 4.3Q
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license