Biology
Biology
10th Edition
ISBN: 9780321794260
Author: Audesirk, Teresa/ Audesirk
Publisher: Pearson College Div
Question
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Chapter 6, Problem 6RQ
Summary Introduction

To compare:

The mechanism of competitive and noncompetitive inhibition of enzymes.

Introduction:

Enzymes are “macromolecular biological catalyst”. They help in the acceleration of chemical reaction. The active site is the region present on an enzyme that provides particular chemistry and shape so that it can fit substrate. It is a groove-like structure present on the surface of an enzyme whose structure changes when it attaches to the substrate. Certain molecules inhibit this reaction by binding to the sites present on enzyme these molecules are known as inhibitors. The binding of the inhibitor on the active site disrupts the functioning of the enzyme.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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