Pathophysiology - E-Book
Pathophysiology - E-Book
6th Edition
ISBN: 9780323510424
Author: Banasik, Jacquelyn L.
Publisher: Saunders
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Chapter 6, Problem 6KQ
Summary Introduction

To describe: What are the available methods of genetic testing?

Introduction: A type of medical test that is involved in studying an individual’s DNA is known as a genetic test. It involves the identification of modifications in genes, chromosomes, or proteins. It is carried out to identify genetic differences or susceptibility to specific abnormalities or diseases. It is used to rule out or confirm the suspected genetic condition. It is also used to determine the chances of developing a genetic disorder.

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Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible.  Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…
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