Concept explainers
To review:
The map distance between the genes his-5 and lys-1 using two methods of calculations, where one method considers double crossover while the second does not, and determine which method gave the highest value.
Frequency of single crossover between two genes.
Nonparental ditypes (NPD) expected from the cross. Whether positive interference is happening in this case.
Introduction:
Map distance is used to estimate the distance between two genes present in a chromosome. Its unit is map units (mu). Double crossovers cause the formation of nonparental ditypes. Positive interference is a genetic phenomenon due to which a crossover occurring in one region of chromosome decreases the possibility of a second crossover near it.
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