BROOKER BIO 3-HOLE PUNCH W/CONNECT BUND
5th Edition
ISBN: 9781264065615
Author: BROOKER
Publisher: MCGRAW-HILL LEARNING SOLN.(CC)
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Chapter 58, Problem 6TY
Summary Introduction
Introduction: Ecologists MacArthur and Wilson proposed a comprehensive model for succession on new islands. This was called the equilibrium model of island biogeography. Succession occurs by slow and gradual development, starting from a sterile beginning.
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Outline a method for using apomixis to maintain feminized CannabisAssume apomixis is controlled by a single dominant gene. You can choose the type of apomixis: obligate or facultative, gametophytic or sporophytic. Discuss advantages and disadvantages of your proposed method.
Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug:
(a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate)
(b) Estimate the time for maximum plasma concentration (tmax).
(c) Estimate the maximum plasma concentration (Cmax).
(d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.)
(e)…
Chapter 58 Solutions
BROOKER BIO 3-HOLE PUNCH W/CONNECT BUND
Ch. 58.1 - Prob. 1CCCh. 58.3 - Prob. 1CCCh. 58.3 - Inhibition implies that competition exists between...Ch. 58.4 - Prob. 1CSCh. 58.4 - Prob. 1CCCh. 58.4 - Prob. 1EQCh. 58.4 - Prob. 2EQCh. 58.4 - CoreSKILL What did the researchers conclude about...Ch. 58.5 - Core Skill: Connections In the two food chains...Ch. 58.5 - Prob. 1CC
Ch. 58.5 - Prob. 2CSCh. 58 - Prob. 1TYCh. 58 - Prob. 2TYCh. 58 - Which evidence suggests that more diverse...Ch. 58 - The process of primary succession occurs a. around...Ch. 58 - Prob. 5TYCh. 58 - Prob. 6TYCh. 58 - Prob. 7TYCh. 58 - Prob. 8TYCh. 58 - Prob. 9TYCh. 58 - Prob. 10TYCh. 58 - Prob. 1CQCh. 58 - Prob. 2CQCh. 58 - Core Concept: Systems In the nutrient-poor...Ch. 58 - List some possible ecological disturbances, their...Ch. 58 - Prob. 2COQ
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