CONNECT ACCESS FOR BIOL 01204 <C>
CONNECT ACCESS FOR BIOL 01204 <C>
12th Edition
ISBN: 9781264443123
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 54, Problem 4U
Summary Introduction

Introduction:

The clutch size is defined as the number of eggs produced by the birds in a nest. There is a relationship in the clutch size and offspring size in which, as the clutch size increases the size of the offspring decreases.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

Chapter 54 Solutions

CONNECT ACCESS FOR BIOL 01204 <C>

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