BIOLOGY 12E CONNECT ACCESS CARD
BIOLOGY 12E CONNECT ACCESS CARD
12th Edition
ISBN: 9781264938513
Author: Raven
Publisher: MCG
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Chapter 53, Problem 4U
Summary Introduction

Introduction:

Migration is a process by which animals and birds move from one place to another. It is done to avoid harsh conditions or resource unavailability. Sometimes birds migrate to very long distances and then return back home when environmental conditions are favorable. Migration is done with the help of environmental cues that helps an organism to remember the path. Orientation and navigation are two important tools that help an organism to migrate.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.
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