Biological Science
5th Edition
ISBN: 9780321743671
Author: Scott Freeman
Publisher: PEARSON
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Chapter 51, Problem 12TYU
Summary Introduction
To review:
Production of unlimited B cell receptors (BCRs), T cell receptors (TCRs) and antibodies by recombinant DNA (deoxyribonucleic acid) technology.
Introduction:
There are millions of diverse TCRs, BCRs and antibodies in our body. All of them are highly specific for a particular epitope. TCR consist of two α chains and two β chains whereas BCR and antibody consist of two identical heavy chains and two identical light chains. All three of them contains variable regions and constant regions. Ability to recognize a specific epitope is based on the fact that they have unique variable region for every epitope, leading to diversity in TCRs, BCRs and antibodies.
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