BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 50, Problem 4S
Toll-like receptors have been found in a wide variety of organisms, including both protostomes and deuterostomes, and now in cnidarians. In addition, parts of the signaling system have been found in a wide variety of organisms as have parts of the complement system. What does this say about the evolution of innate immunity?
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For some time there has been evidence that the Bacille Calmette-Guérin (BCG) vaccine provides protection not
only against the target disease (Mycobacterium tuberculosis), but also enhances responses to other infections
(such as Staphylococcus aureus and Candida albicans). Do you think the enhanced response to other
infections, as described, is due to innate responses to the vaccine or adaptive responses? Explain your answer.
In vertebrates, complement activation generally involves a pathogen recognition step followed by a proteolytic cascade that produces the effector proteins that function in opsonization, membrane attack, and inflammation.
Which of these is likely to be the most evolutionarily primitive aspect of the complement system?
Which pathway of complement initiation is likely to be the one that most recently evolved?
Which of the following is NOT a mechanism used by the immune system to fight
multicellular parasites?
Select one:
a. Antibodies coating the pathogen surface bind to FcRs on mast cells, causing release of granule contents onto
surface, and damage the parasite.
b. Crosslinking of antibody binding to FceRI on eosinophils cells triggers release of granules, causing smooth
muscle contractions.
Muscle contractions in the mucosal tracts causes sneezing, coughing, vomiting or diarrhea, dislodging the
parasite.
d. The parasite is killed and broken down extracellularly, and then phagocytosed by macrophages.
C.
Chapter 50 Solutions
BIOLOGY
Ch. 50.1 - Prob. 1LOCh. 50.1 - Prob. 2LOCh. 50.1 - Prob. 3LOCh. 50.2 - Prob. 1LOCh. 50.2 - Prob. 2LOCh. 50.2 - Prob. 3LOCh. 50.3 - Prob. 1LOCh. 50.3 - Prob. 2LOCh. 50.4 - Explain how antibody diversity is generated.Ch. 50.4 - Prob. 2LO
Ch. 50.4 - Prob. 3LOCh. 50.5 - Define autoimmune diseases.Ch. 50.5 - Prob. 2LOCh. 50.6 - Explain antigenantibody reactions in the ABO blood...Ch. 50.6 - Prob. 2LOCh. 50.6 - Prob. 3LOCh. 50.7 - Prob. 1LOCh. 50.7 - Prob. 2LOCh. 50 - How would a high level of HCG present in a urine...Ch. 50 - What would happen if an NK cell killed a virally...Ch. 50 - Prob. 2IQCh. 50 - Prob. 3IQCh. 50 - Prob. 4IQCh. 50 - Cells that target and kill body cells infected by...Ch. 50 - Structures on invading cells recognized by the...Ch. 50 - Which one of the following acts as the alarm...Ch. 50 - Prob. 4UCh. 50 - Receptors that trigger innate immune responses a....Ch. 50 - Diseases in which the persons immune system no...Ch. 50 - Suppose that a new disease is discovered that...Ch. 50 - You start a new job in a research lab. The lab...Ch. 50 - In comparing T-cell receptors and immunoglobulins...Ch. 50 - If you have type AB blood, which of the following...Ch. 50 - Suppose that you get a paper cut while studying....Ch. 50 - If you wanted to cure allergies by bioengineering...Ch. 50 - Why do we need to be repeatedly vaccinated for...Ch. 50 - Prob. 7ACh. 50 - Suppose you take a job in the marketing department...Ch. 50 - Prob. 2SCh. 50 - Prob. 3SCh. 50 - Toll-like receptors have been found in a wide...
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- In Lubeck, Germany, in 1930, a group of 251 infants was accidentally administered a tainted vaccine for tuberculosis that contained live Mycobacterium tuberculosis. This vaccine was administered orally, directly exposing the infants to the deadly bacterium. Many of these infants contracted tuberculosis, and some died. However, 44 of the infants never contracted tuberculosis. Based on your knowledge of the innate immune system, what innate defenses might have inhibited M. tuberculosis enough to prevent these infants from contracting the disease?arrow_forwardSponges display nonspecific immunity. In an experiment, the cells of two different sponges were mixed and placed within a petri dish. The cells from each sponge sorted and arranged themselves together according to organism. What does this characteristic demonstrate? A. Sponges have memory T-cells and share a more recent common ancestor with vertebrates than other invertebrates. B. The experiment provides evidence for the speed of evolution and the use of specific immunity within the organism. C. Sponges have an ability to recognize their own cells as a characteristic of acquired immunity. D. Sharing genetic information from cell to cell is possible by means of receptors and protein-lined pits.arrow_forwardWhat term describes microbial molecules of pathogens such as peptidoglycan and LPS that can trigger the innate immune system to respond? O 1) PAMP O 2) epitope O 3) antigen O 4) haptenarrow_forward
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- Which of the following is not true for a natural killer cell? A) do not undergo rearrangement of receptor genes B) develop in the thymus c) stimulated (activated) by IFN-a and other cytokines D) lack of NK cells can lead to severe viral infections Question 6 Represents innate immune system receptors A Randomly arranged B) Germline encoded c) cross-reactive D) CLP encoded is determined by specific carbohydrate groupsarrow_forwardHuman immune system a) Pathogen-associated molecular patterns are conserved molecular structures produced by microorganisms, but not by host cells. b) A virus-infected host cell that displays a viral antigen via MHC class I molecules may become a target of cytotoxic T cells. c) Secreted MHC Class I proteins present in blood plasma can function as opsonins. d) Both (a) and (b) are correct and (c) is incorrect e) Statements (a), (b) and (c) are all correctarrow_forwardWhat kind of immune responses do insects have a) adaptive immunity only b) innate immunity only c) they have innate and adaptive immunity but the adaptive immune system has fewer cells than that of vertebrates d innate and adaptive immunityarrow_forward
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