ANATOMY & PHYSIOLOGY LL\AC
9th Edition
ISBN: 9781264325948
Author: SALADIN
Publisher: MCG
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Chapter 5, Problem 9TYR
Summary Introduction
Introduction:
The external ear of animals and humans is composed of a flexible rubbery matrix cartilage. The external ear is a stiff connective tissue, which is flexible in nature for folding and releasing the ear.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 5 Solutions
ANATOMY & PHYSIOLOGY LL\AC
Ch. 5.1 - Classify each of the following into one of the...Ch. 5.1 - What are tissues composed of in addition to cells?Ch. 5.1 - Prob. 3BYGOCh. 5.1 - Prob. 4BYGOCh. 5.1 - Two names for the branch of biology concerned with...Ch. 5.1 - Prob. 2AYLOCh. 5.1 - The roles of cells, matrix, fibers, and ground...Ch. 5.1 - Primary germ layers of the embryo and their...Ch. 5.1 - Prob. 5AYLOCh. 5.2 - Distinguish between simple and stratified...
Ch. 5.2 - Prob. 6BYGOCh. 5.2 - Prob. 7BYGOCh. 5.2 - Prob. 8BYGOCh. 5.2 - Prob. 1AYLOCh. 5.2 - Prob. 2AYLOCh. 5.2 - 5.2 Epithelial Tissue 3. Defining characteristics...Ch. 5.2 - Prob. 4AYLOCh. 5.2 - Prob. 5AYLOCh. 5.2 - Prob. 6AYLOCh. 5.2 - Prob. 7AYLOCh. 5.2 - Prob. 8AYLOCh. 5.2 - Prob. 9AYLOCh. 5.3 - What features do most or all connective tissues...Ch. 5.3 - Prob. 10BYGOCh. 5.3 - Prob. 11BYGOCh. 5.3 - Prob. 12BYGOCh. 5.3 - Discuss the difference between dense regular and...Ch. 5.3 - Prob. 14BYGOCh. 5.3 - Prob. 15BYGOCh. 5.3 - Prob. 1AYLOCh. 5.3 - Prob. 2AYLOCh. 5.3 - Prob. 3AYLOCh. 5.3 - Prob. 4AYLOCh. 5.3 - Prob. 5AYLOCh. 5.3 - 5.3 Connective Tissue 6. The appearance,...Ch. 5.3 - Prob. 7AYLOCh. 5.3 - Prob. 8AYLOCh. 5.3 - Prob. 9AYLOCh. 5.3 - Prob. 10AYLOCh. 5.3 - 5.3 Connective Tissue 11. Why blood is classified...Ch. 5.4 - Prob. 16BYGOCh. 5.4 - Prob. 17BYGOCh. 5.4 - Prob. 18BYGOCh. 5.4 - Prob. 1AYLOCh. 5.4 - Prob. 2AYLOCh. 5.4 - Prob. 3AYLOCh. 5.4 - 5.4 Nervous and Muscular TissuesExcitable Tissues...Ch. 5.4 - Prob. 5AYLOCh. 5.5 - Prob. 19BYGOCh. 5.5 - Prob. 20BYGOCh. 5.5 - Prob. 21BYGOCh. 5.5 - Prob. 22BYGOCh. 5.5 - Prob. 23BYGOCh. 5.5 - Prob. 1AYLOCh. 5.5 - Prob. 2AYLOCh. 5.5 - Prob. 3AYLOCh. 5.5 - Prob. 4AYLOCh. 5.5 - Prob. 5AYLOCh. 5.5 - Prob. 6AYLOCh. 5.5 - Prob. 7AYLOCh. 5.5 - 5.5 Cell Junctions, Glands, and Membranes 8....Ch. 5.5 - 5.5 Cell Junctions, Glands, and Membranes 9....Ch. 5.5 - Prob. 10AYLOCh. 5.6 - Distinguish between differentiation and...Ch. 5.6 - Prob. 25BYGOCh. 5.6 - Prob. 26BYGOCh. 5.6 - Distinguish between regeneration and fibrosis....Ch. 5.6 - Prob. 1AYLOCh. 5.6 - Prob. 2AYLOCh. 5.6 - 5.6 Tissue Growth, Development, Repair, and...Ch. 5.6 - Prob. 4AYLOCh. 5.6 - Prob. 5AYLOCh. 5.6 - Prob. 6AYLOCh. 5.6 - Prob. 7AYLOCh. 5.6 - 5.6 Tissue Growth, Development, Repair, and...Ch. 5 - Transitional epithelium is found is a. the urinary...Ch. 5 - Prob. 2TYRCh. 5 - Which of these is a primary germ layer? a....Ch. 5 - A seminiferous tubule of the testis is lined with...Ch. 5 - Prob. 5TYRCh. 5 - A fixative serves to a. stop tissue decay. b....Ch. 5 - Prob. 7TYRCh. 5 - Prob. 8TYRCh. 5 - Prob. 9TYRCh. 5 - Prob. 10TYRCh. 5 - Prob. 11TYRCh. 5 - Prob. 12TYRCh. 5 - Prob. 13TYRCh. 5 - Prob. 14TYRCh. 5 - Tendons and ligaments are made mainly of the...Ch. 5 - Prob. 16TYRCh. 5 - Prob. 17TYRCh. 5 - Fibers and ground substance make up the ______ of...Ch. 5 - A/An _______ adult stem cell can differentiate...Ch. 5 - Prob. 20TYRCh. 5 - Prob. 1BYMVCh. 5 - Prob. 2BYMVCh. 5 - State a meaning of each word element, and give a...Ch. 5 - Prob. 4BYMVCh. 5 - Prob. 5BYMVCh. 5 - State a meaning of each word element, and give a...Ch. 5 - Prob. 7BYMVCh. 5 - Prob. 8BYMVCh. 5 - Prob. 9BYMVCh. 5 - Prob. 10BYMVCh. 5 - The esophagus is protected from abrasion by a...Ch. 5 - Prob. 2WWTSCh. 5 - Prob. 3WWTSCh. 5 - Prob. 4WWTSCh. 5 - Prob. 5WWTSCh. 5 - Prob. 6WWTSCh. 5 - Prob. 7WWTSCh. 5 - Prob. 8WWTSCh. 5 - Prob. 9WWTSCh. 5 - Prob. 10WWTSCh. 5 - A woman in labor is often told to push. In doing...Ch. 5 - A major tenet of the cell theory is that all...Ch. 5 - Prob. 3TYCCh. 5 - The epithelium of the respiratory tract is mostly...Ch. 5 - Which do you think would heal faster, cartilage or...
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