ORGANIC CHEMISTRY (LOOSELEAF)
ORGANIC CHEMISTRY (LOOSELEAF)
6th Edition
ISBN: 9781260475630
Author: SMITH
Publisher: MCG
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Chapter 5, Problem 70P

Artemisinin and mefloquine are widely used antimalarial drugs. A ball-and-stick model of artemisinin appears on the cover of this text.

Chapter 5, Problem 70P, 
5.67 Artemisinin and mefloquine are widely used antimalarial drugs. A ball-and-stick model of

a. Locate the stereogenic centers in both drugs.

b. Label each stereogenic center in mefloquine as R or S .

c. What is the maximum number of stereoisomers possible for artemisinin?

d. How are the N atoms in mefloquine hybridized?

e. Can two molecules of artemisinin intermolecularly hydrogen bond to each other?

f. What product is formed when mefloquine is treated with HCl ?

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