Essentials of Human Anatomy and Physiology (Custom)
15th Edition
ISBN: 9781269752862
Author: Marieb
Publisher: PEARSON
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Chapter 5, Problem 36CAQ
A 75-year-old woman and her 9-year-old granddaughter were in a car accident in which both sustained trauma to the chest while seated next to each other. X-ray images showed that the grandmother had several fractured ribs, but her granddaughter had none. Explain these different findings.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
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Chapter 5 Solutions
Essentials of Human Anatomy and Physiology (Custom)
Ch. 5 - More than one choice may apply. Which of the...Ch. 5 - Prob. 2MCCh. 5 - 3. Which of the following would you expect to be...Ch. 5 - Prob. 4MCCh. 5 - Prob. 5MCCh. 5 - Prob. 6MCCh. 5 - Which parts of the thoracic vertebrae articulate...Ch. 5 - Which of the following bones or bond parts...Ch. 5 - Which bone of the arm corresponds to the femur of...Ch. 5 - More than one choice may apply. Which of the...
Ch. 5 - 11. Match the types of joints the descriptions...Ch. 5 - Match the bone markings listed on the right with...Ch. 5 - Prob. 13SAECh. 5 - What is yellow marrow? How do spongy and compact...Ch. 5 - Prob. 15SAECh. 5 - Prob. 16SAECh. 5 - Prob. 17SAECh. 5 - Prob. 18SAECh. 5 - 19. With one exception, all skull bones are joined...Ch. 5 - What facial bone forms the chin? The cheekbone?...Ch. 5 - 21. Name two ways in which the fetal skull differs...Ch. 5 - 22. How many vertebrae are there in each of the...Ch. 5 - Diagram the normal spinal curvatures and then the...Ch. 5 - Prob. 24SAECh. 5 - Name the major components of the thorax.Ch. 5 - Is a floating rib a true or a false rib? Why are...Ch. 5 - 27. Name the bones of the shoulder girdle.
Ch. 5 - 28. Name all the bones with which the ulna...Ch. 5 - What bones make up each hip bone (coxal bone)?...Ch. 5 - 30. Name the bones of the lower limb from superior...Ch. 5 - Compare the amount of movement possible in...Ch. 5 - Describe the structure of a synovial joint. Use...Ch. 5 - Prob. 33SAECh. 5 - Which structural parts of our vertebrae are most...Ch. 5 - 35. List two factors that keep bones healthy. List...Ch. 5 - A 75-year-old woman and her 9-year-old...Ch. 5 - Prob. 37CAQCh. 5 - After having a severe cold accompanied by nasal...Ch. 5 - Prob. 39CAQCh. 5 - Prob. 40CAQCh. 5 - 42. An X-ray image of the arm of an accident...Ch. 5 - Prob. 42CAQCh. 5 - A patient complains of pain starting in the jaw...Ch. 5 - Prob. 44CAQ
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