The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Question

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Answer 1

Question

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

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Students have asked these similar questions

A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation? The cell membranes are more resistant than normal. An isotonic solution had been added instead of water. A solution of 0.1 M NaCl had been added instead of water. Not enough water had been added to the red blood cell pellet. The man had sickle-cell anaemia.

With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin

Answer 2

Question

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

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Answer 3

Question

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

Answer 6

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

Answer 7

Chapter 5, Problem 1Q

Summary Introduction

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Answer 8

Expert Solution & Answer

Answer to Problem 1Q

Correct answer:

The correct answer are option (c) and option (e).

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Explanation of Solution

Explanation/justification for the correct answer:

Option (c) and option (e) are the features that distinguish T-cell receptors from immunoglobulins.

A T-cell receptor is never secreted subsequent to antigen-encounter. On the contrary naïve B-cells are responsible for antigen encounter. They bind antigens that complement to the antibodies bound to their membranes. These B-cells then directly release antibodies to the bloodstream to bind to antigens. The T-cell receptors bind to antigenic epitopes presented to them in an associated form with the MHC complexes. This is a major difference between immunoglobulins and T-cell receptors. Thus, option (c) is the correct option.

T-cell receptors are used solely for the purpose of antigen recognition and not for effector function. The Fc domain of immunoglobulins is involved in their effector functions, which include a coating over pathogens followed by agglutination reactions and others. The T-cell receptors however are only involved in recognition and binding of the antigenic epitopes. Such binding relay a series of biochemical signaling events to bring out the desired effects. Hence, option (e) is a functional difference between the immunoglobulins and T-cell receptors.

Explanation for the incorrect answer:

Option (a) is a similarity between immunoglobulins and T-cell receptors. Both antibodies and T-cell receptors are generated through somatic rearrangements. The genes of the variable regions in both these families undergo similar rearrangements. Hence, this option is an incorrect choice.

Option (b) states that the T-cell repertoire encompasses a very large degree of diversity. This diversity is attributed to the genetic rearrangements in the variable-gene region that gives rise to many combinations randomly. Similar is the diversity in immunoglobulins. Hence, this choice is a similarity and not a point of distinction.

Option (d) states that the variable region of the T-cell receptors contains complementarity-determining regions that interact with antigen. The variable region in both immunoglobulins and T-cell receptors are involved in the interaction between the antigenic sequences called epitopes. Hence, this option is not a point of difference.

Answer 12

Conclusion

Though encoded by a different family of genes the immunoglobulins and the T-cell receptors both share many features in common yet have some distinct differences.

Answer 13

Ch. 5 - Prob. 1Q Ch. 5 - Prob. 2Q Ch. 5 - Prob. 3Q Ch. 5 - Prob. 4Q Ch. 5 - Prob. 5Q Ch. 5 - Prob. 6Q Ch. 5 - Prob. 7Q Ch. 5 - Prob. 8Q Ch. 5 - Prob. 9Q Ch. 5 - Prob. 10Q

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Videos

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Answer to Problem 1Q

Explanation of Solution

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Chapter 5 Solutions

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Videos

Introduction: The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.

Answer to Problem 1Q

Explanation of Solution

Want to see more full solutions like this?

Chapter 5 Solutions

Introduction:

The T-cell receptors are entities present on the surface of T-cells that recognize and bind to antigenic peptides associated with MHC complexes.