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In Drosophila, the autosomal recessive dp allele of the dumpy gene produces short, curved wings, while the autosomal recessive allele bw of the brown gene causes brown eyes. In a testcross using females heterozygous for both of these genes, the following results were obtained: wild-type wings, wild-type eyes 178 wild-type wings, brown eyes 185 dumpy wings, wild-type eyes 172 dumpy wings, brown eyes 181
In a testcross using males heterozygous for both of these genes, a different set of results was obtained: wild-type wings, wild-type eyes 247 dumpy wings, brown eyes 242
a. | What can you conclude from the first testcross? |
b. | What can you conclude from the second testcross? |
c. | How can you reconcile the data shown in parts (a) and (b)? Can you exploit the difference between these two sets of data to devise a general test for synteny in Drosophila? |
d. | The genetic distance between dumpy and brown is 91.5 m.u. How could this value be measured? |
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