Lehninger Principles of Biochemistry 7E & SaplingPlus for Lehninger Principles of Biochemistry 7E (Six-Month Access)
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ISBN: 9781319125882
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 5, Problem 12P
Summary Introduction
To determine: The reason why monoclonal antibody binds to G-actin but not to F-actin based on the epitope recognized by the antibody.
Introduction:
Antibodies produced usually by an infection and immunization are polyclonal because natural antigens have multiple epitopes. On the other hand, monoclonal antibodies (mAb) are the monospecific antibodies. The mAb are produced from the clone of single lymphocytes directed against a single antigenic determinant or epitope.
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