Campbell Biology & Alkaline Vents Supplemental Materials for Campbell Biology & Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology Package
Campbell Biology & Alkaline Vents Supplemental Materials for Campbell Biology & Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology Package
1st Edition
ISBN: 9780133984293
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 49, Problem 2TYU
Summary Introduction

Introduction:

The brain is a complex system that controls various activities. The limbic system is a set of brain structures that are present beneath the thalamus. The limbic system is involved in emotion, memory, learning, and motivation. Amygdala is an almond-shaped mass of nuclei located near the base of the cerebrum. It controls the emotional memory such as a frightening event that can trigger faster heart rate, sweating or fear. The medulla oblongata is the lower part of the brain stem. It deals with the autonomic functions, homeostatic functions such as breathing, heart rate, and blood pressure. The cerebellum is a part of the hindbrain. It controls involuntary activities such as blood circulation and coordinates motor activities such as locomotion.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

Chapter 49 Solutions

Campbell Biology & Alkaline Vents Supplemental Materials for Campbell Biology & Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology Package

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