LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 9781319145125
Author: Sadava
Publisher: MAC HIGHER
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Chapter 48.4, Problem 2R
Summary Introduction
To review:
The consequence of transfusion of red blood cells into the patient that are stored in a blood bank
Introduction:
1, 3-BPG (1, 3-bisphosphoglycerate) is formed during glycolysis as an intermediate product. 1, 3-BPG fulfills the energy requirement of cells of the body. The conversion of 1, 3-BPG to 2, 3-BPG takes place in the red blood cells as it helps in regulation of hemoglobin. It reduces the affinity of deoxygenated hemoglobin for oxygen by binding to it due to which more of the bound oxygen is released by the hemoglobin molecules.
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*Example 2: Tracing the path of an autosomal dominant trait
Trait: Neurofibromatosis
Forms of the trait:
The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein
neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous
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cancerous form. i
The recessive form is a normal protein - in other words, no neurofibromatosis.moovi
A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not
indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis
allele, and the letter "n" for the normal allele.
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Chapter 48 Solutions
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