CAMPBELL BIOLOGY MOD MASTERING (18 WEEK)
12th Edition
ISBN: 9780136920335
Author: Urry
Publisher: PEARSON
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Question
Chapter 48.1, Problem 1CC
Summary Introduction
To explain: The difference in structures and functions of axon and dendrites.
Concept introduction:
Neurons are the nerve cells that transfer information within the body. A neuron is made up of dendrites and an axon. Communication by the neurons is sent as electrical signals for long distances and chemical signals for short distances.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
MAKE SURE ANSWERS HAVE UNITS if appropriate.
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
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The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 48 Solutions
CAMPBELL BIOLOGY MOD MASTERING (18 WEEK)
Ch. 48.1 - Prob. 1CCCh. 48.1 - Describe the basic pathway of information flow...Ch. 48.1 - WHAT IF? How might increased branching of an axon...Ch. 48.2 - Under what circumstances could ions flow through...Ch. 48.2 - WHAT IF? Suppose a cell's membrane potential...Ch. 48.2 - MAKE CONNECTiONS Review Figure 7.10, which...Ch. 48.3 - How do action potentials and graded potentials...Ch. 48.3 - In multiple sclerosis (from the Greek skleros,...Ch. 48.3 - How do both negative and positive feedback...Ch. 48.3 - WHAT IF? Suppose a mutation caused gated sodium...
Ch. 48.4 - Prob. 1CCCh. 48.4 - Some pesticides inhibit acetylcholinesterase, the...Ch. 48.4 - Prob. 3CCCh. 48 - How would severing an axon affect the flow of...Ch. 48 - Suppose you placed an isolated neuron in a...Ch. 48 - Prob. 48.3CRCh. 48 - Prob. 48.4CRCh. 48 - Level 1: Knowledge/Comprehension 1. What happens...Ch. 48 - Level 1: Knowledge/Comprehension 1. What happens...Ch. 48 - Where are neurotransmitter receptors located? (A)...Ch. 48 - Why are action potentials usually conducted in one...Ch. 48 - Which of the following is the most direct result...Ch. 48 - Suppose a particular neurotransmitter causes an...Ch. 48 - WHAT IF? Ouabain, a plant substance used in some...Ch. 48 - Prob. 8TYUCh. 48 - DRAW IT Suppose a researcher inserts a pair of...Ch. 48 - EVOLUTION CONNECTION An action potential is an...Ch. 48 - Prob. 11TYUCh. 48 - WRITE ABOUT A THEME: ORGANIZATION In a short essay...Ch. 48 - Prob. 13TYU
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