BIOLOGICAL SCIENCE
7th Edition
ISBN: 9780135276822
Author: Freeman
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Question
Chapter 47, Problem 14PIAT
Summary Introduction
To analyze:
The pill’s effects on the normal hormonal function in the body in each of the following:
(a) Maturation of a follicle
(b) Thickening of the uterine lining during the follicular phase
(c) Probability of ovulation
(d) Volume of menstrual fluid
Introduction:
The FSH (follicle-stimulating hormone) is secreted by the anterior pituitary and regulates the pubertal maturation, growth, and development. It works along with LH (luteinizing hormone) in the reproductive system. The pill’s mechanism was confirmed by the scientists by measuring the plasma hormone levels before and after the use of the pill. Given below is a graph representing the different levels of progesterone at different pill concentrations. Single asterisk (*) signifies P < 0.05, double asterisks (&) signify P **lt; 0.01, and triple asterisks (&*) signify P **lt; 0.001.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Please answer the following chart so I can understand how to do it.
Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 47 Solutions
BIOLOGICAL SCIENCE
Ch. 47 - Prob. 1TYKCh. 47 - Prob. 2TYKCh. 47 - Prob. 4TYKCh. 47 - Summarize the experimental evidence that Daphnia...Ch. 47 - Prob. 6TYUCh. 47 - 7. How do spermatogenesis and oogenesis in humans...Ch. 47 - 8. Give examples of negative feedback and positive...Ch. 47 - Prob. 9TYPSSCh. 47 - Prob. 11PIATCh. 47 - Prob. 12PIAT
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- 3. In the tomato, red fruit (O+) is dominant over orange fruit (0), and yellow flowers (W+) are dominant over white flowers (w). A cross was made between true-breeding plants with red fruit and yellow flowers, and plants with orange fruit and white flowers. The F₁ plants were then crossed to plants with orange fruit and white flowers, which produced the following results: a. b. 333 red fruit, yellow flowers 64 red fruit, white flowers 58 orange fruit, yellow flowers 350 orange fruit, white flowers Conduct a chi-square analysis to demonstrate that these two genes DO NOT assort independently. Make sure to interpret the P value obtained from your chi-square test. Calculate and provide the map distance (in map units) between the two genes.arrow_forwardName: Date: Investigation: Is a dog more closely related to a coyote or a wolf? Gray Wolf Species Name: Canis lupus Color: Light gray to black Size: 80-120 pounds, 2.5 feet tall Appearance: broad snout, round ears, long tail Coyote Species Name: Canis latrans Color: Light gray to brown Size: 20-50 pounds, 1.5 feet tall Appearance: narrow snout, pointed ears, long tail Dog, Alaskan Malamute Species Name: Canis lupus familiaris Color: Gray and white or brown and white Size: 70-80 pounds, 2 feet tall Appearance: broad snout, round ears, long tail 1. Examine the images and descriptions above. Underline any similarities between the dog and the wolf. Place a star next to any coyote traits that are similar to the dog. 2. Based on appearance alone, which do you think is the most closely related to a dog? www.biologycorner.comarrow_forwardyu yeuwyuyuierydtgcygucygzycghjcygyugfyudguygcywgduycgyudgs ygarrow_forward
- According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) # of women BRCA1 genotype BB 390 Bb bb 12pt v 10 0 V Paragraph B IUA BIUA > V T² v <arrow_forwardCase Study—Ella Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch. Categories of Sandwich Options (Top of the screen) Breads Spreads Cheeses Vegetables Proteins Specific food items to select White Bread 6-inches Honey Mustard Provolone LettuceTomatoBell Peppers Turkey Part A - Reading Nutrition Facts Panels for Total Kilocalories How many total kilocalories are in Ella’s sandwich? _______ kcal ? Part B - Reading Nutrition Facts Panels for…arrow_forwardCase Study—Ella Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch. Categories of Sandwich Options (Top of the screen) Breads Spreads Cheeses Vegetables Proteins Specific food items to select White Bread 6-inches Honey Mustard Provolone LettuceTomatoBell Peppers Turkey Part A - Reading Nutrition Facts Panels for Total Kilocalories How many total kilocalories are in Ella’s sandwich exactl ______kcal ? Part B - Reading Nutrition Facts Panels for…arrow_forward
- In humans, red-green color blindness is recessive and X-linked, whereas albinism is recessive and autosomal. What types of children can be produced as the result of marriage between two homozygous parents, a normal-vision albino woman and a color-blind, normal male?arrow_forwardIn Drosophila, an X linked recessive mutation, scalloped (sd), causes irregular wing margins. Diagram the F1 and F2 results if a (a) scalloped female is crossed with a normal male; (b) a scalloped male is crossed with a normal female (assume the female is homozygous). Compare these results to what you would find if the trait was not sex linked.arrow_forwardCase Study—Ella Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch. Categories of Sandwich Options (Top of the screen) Breads Spreads Cheeses Vegetables Proteins Specific food items to select White Bread 6-inches Honey Mustard Provolone LettuceTomatoBell Peppers Turkey Part A - Reading Nutrition Facts Panels for Total Kilocalories How many total kilocalories are in Ella’s sandwich exactl ______kcal ? Part B - Reading Nutrition Facts Panels for…arrow_forward
- C MasteringHealth MasteringNu × session.healthandnutrition-mastering.pearson.com/myct/itemView?assignment ProblemID=17465255&attemptNo=1&offset=prevarrow_forwardBiopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forwardGlitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.arrow_forwardarrow_back_iosSEE MORE QUESTIONSarrow_forward_ios
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Embryology | Fertilization, Cleavage, Blastulation; Author: Ninja Nerd;https://www.youtube.com/watch?v=8-KF0rnhKTU;License: Standard YouTube License, CC-BY