Campbell Biology Custom Stony Brook 10 Th Edition
Campbell Biology Custom Stony Brook 10 Th Edition
10th Edition
ISBN: 9781269870818
Author: Reece Urry Cain Wasserman Minorsky Jackson
Publisher: PEARSON
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Chapter 45.3, Problem 2CC
Summary Introduction

To review: How the levels of corticosteroids are affected by the decrease in corticosteroid receptors.

Concept introduction: Corticosteroids are one of the classes of steroid hormones that are produced in the adrenal glands. A decrease in corticosteroid receptors in the hypothalamus would lead to a condition where the levels of the corticosteroids will be elevated.  The main reasons behind such reactions are failure in feedback inhibition on the hypothalamic neurons that induces the secretion of (cortisol) that stimulates the release of ACTH from the anterior pituitary.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
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