Laboratory Manual for Human Anatomy & Physiology (Cat Version)
Laboratory Manual for Human Anatomy & Physiology (Cat Version)
4th Edition
ISBN: 9781259864612
Author: Martin
Publisher: MCGRAW-HILL HIGHER EDUCATION
bartleby

Concept explainers

Question
Book Icon
Chapter 43, Problem 1PL
Summary Introduction

Introduction:

Antigens are the substances which are specifically bounded by antibodies. It is a structural molecule that binds specifically to an antibody only in the form of a native antigen. It evokes an immune response either alone or forming a complex with larger molecules and that is capable of binding with a product of the immune response.

Expert Solution & Answer
Check Mark

Answer to Problem 1PL

Correct answer:

The correct answer is option (a) on the red blood cell membranes.

Explanation of Solution

Explanation/justification for the correct answer:

Option (a) on the red blood cell membranes. The blood typing involves the identifying of protein substances called antigens, present on the outer surface of the red blood cell membranes. These include the antigens of the ABO group and those of the Rh group. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells. These chains are attached to proteins and lipids that lie over the surface of the red blood cell membrane. So, the correct answer is option (b).

Explanation for incorrect answer:

Option (b) within the red blood cell nucleus. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells and not within the nucleus. Also, the red blood cells are devoid of nucleus. So, this is an incorrect option.

Option (c) within the red blood cell cytosol. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells and not within the cytosol. So, this is an incorrect answer.

Option (d) on the surface of red blood cell ribosome. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells. These chains are attached to proteins and lipids that lie over the surface of the red blood cell membrane and not ribosome. So, this is an incorrect answer.

Conclusion

Thus, the antigens related to the ABO blood group are located on the surface of the red blood cell membranes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data  (b) k, ka, B1, and AUC* for the po data  (c) k, ka, B1, and AUC* for the ip data  (d) relative bioavailability for po vs ip, Fpo/Fip  (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip    MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.
2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0  Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present.  Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Text book image
Body Structures & Functions
Biology
ISBN:9781285695495
Author:Scott
Publisher:Cengage
Text book image
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Text book image
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Text book image
Ebk:Nutrition & Diet Therapy
Health & Nutrition
ISBN:9780357391747
Author:DEBRUYNE
Publisher:Cengage
Text book image
Basic Clinical Laboratory Techniques 6E
Biology
ISBN:9781133893943
Author:ESTRIDGE
Publisher:Cengage