Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781260081848
Author: Robert Brooker
Publisher: Mcgraw-hill Higher Education (us)
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Chapter 42.3, Problem 1TYK
Summary Introduction

Introduction:

Survival is the key factor which is important for the continuation of the species. Every organism in this world has evolved many survivability related behaviors, which help in minimizing the threat to their disappearance and loss of genes.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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