Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 42.3, Problem 1CT
In 2017, scientists used CRISPR Cas9 DNA editing to repair a defective gene in a human embryo. Should this be allowed? Is preventing disease and disability in the children sufficient justification for changing the genetic makeup of a human being? What about “designer” children whose DNA may be changed solely to produce an athlete or supermodel body type?
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The first attempts at gene therapy began in 1990 with the treatment of a young girl with a genetic disorder abbreviated SCID. What does SCID stand for? In the context of SCID, what does ADA stand for?
I believe that there are many good things that can come out of people getting to design their baby’s genetic material. But there are also many bad things as well. From the article by Bio medical about the pros and cons of having a designer baby it states that a pro is that this type of engineering can “ might help prevent genetic diseases such as Alzheimer’s, Huntington’s Disease, down syndrome, Spinal Muscular Atrophy, and many others”. I think that it is great that we could get rid of Alzheimer’s due to how destructive it can be to the people that suffer it. But I think the other diseases that it can eliminate is horrible due to them making our world a more unique place such as people with autism, Down syndrome. By doing this it could eliminate the whole population of people with disabilities community and make everyone “normal”. Another bad that I found in the article Ethics of designer babies which states that a major flaw for these babies is “designer baby technologies suggest…
What is the main purpose of genome-wide association studies (GWAS)? How can information from GWAS be used to inform scientists and physicians about genetic diseases?
Chapter 42 Solutions
Biology
Ch. 42.1 - Prob. 1TCCh. 42.1 - Prob. 2TCCh. 42.1 - Prob. 1CSCCh. 42.1 - Prob. 1CYLCh. 42.1 - Prob. 2CYLCh. 42.1 - Prob. 3CYLCh. 42.2 - Mammalian sperm dont live very long after...Ch. 42.2 - Prob. 1TCCh. 42.2 - Prob. 1HYEWCh. 42.2 - describe the human male and female reproductive...
Ch. 42.2 - explain how hormonal interactons control...Ch. 42.2 - describe spermatogenesis and oogenesis, the...Ch. 42.3 - In 2017, scientists used CRISPR Cas9 DNA editing...Ch. 42.3 - describe the principal methods of contraception,...Ch. 42.3 - Prob. 2CTCh. 42 - In humans, sperm are produced in the a....Ch. 42 - In humans, fertilization usually occurs in the a....Ch. 42 - Prob. 3MCCh. 42 - Prob. 4MCCh. 42 - Prob. 5MCCh. 42 - Reproduction by a single animal, without the need...Ch. 42 - In mammals, the male gonad is called...Ch. 42 - Prob. 3FIBCh. 42 - Prob. 4FIBCh. 42 - Prob. 5FIBCh. 42 - Oocytes develop in a multicellular structure, the...Ch. 42 - Describe the advantages and disadvantages of...Ch. 42 - Compare the structures of the egg and sperm. What...Ch. 42 - Prob. 3RQCh. 42 - List the structures, in order, through which a...Ch. 42 - Name the three accessory glands of the male...Ch. 42 - Prob. 6RQCh. 42 - Prob. 1AC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Although it is well known that X-rays cause mutations, they are routinely used to diagnose medical problems, including potential tumors, broken bones, and dental cavities. Why is this done? What precautions need to be taken?arrow_forwarda) Write a short description of why someone would choose to write about wolves vs. dogs. Make an argument for why this topic is interesting. b) Write a short description of why someone would choose this paper below of comparative analysis of the blood transcriptomes between wolves. How does this paper relate to wolves vs. dogs? c) How can you tell that this is a primary research paper and not a review article?arrow_forwardSome people have argued that editing the genomes of human embryos is ethically defensible as long as the embryos are not allowed to develop past an early stage and thus will never result in the birth of genetically modified humans. Others have argued that no genome editing should be carried out on human embryos. Present arguments for and against using genome editing on human embryos.arrow_forward
- Who should be treated by gene therapy? What criteria are used to determine if a person is a candidate for gene therapy? Should gene therapy be used for cosmetic purposes or to improve athletic performance?arrow_forwardDo all of them True/False 31) The process by which an electrical charge is used to introduce DNA into a cell to produce a transgenic organism is called electroporation.Answer: 32) Reproductive cloning is used to produce large amounts of mammalian proteins from transgenic agricultural animals such as cattle.Answer: 33) In gene addition, homologous recombination is used to remove the original gene and replace it with the cloned gene.Answer: 34) All stem cells have the potential to differentiateAnswer: 35) A bone marrow transplant involves the transfer of multipotent stem cellsAnswer: 36) The fact that in mammalian systems multiple genes may compensate for the loss of a gene is called gene redundancy.Answer:arrow_forwardBeing able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…arrow_forward
- Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…arrow_forwardTo create genetically modified organisms (often called GMOS) scientists directly manipulate the genes of an organism, often by inserting or deleting one or more genes. The inserted gene is usually from another species. The purpose of this manipulation is to give the target organism and its offspring a new trait that improves it in some way. The improvement might, for example, give the organism higher vitamin content. The process is called genetic engineering. 1. What are genetically modified organisms? 2. What is Genetic engineering?arrow_forwardWhat is reproductive cloning? How is it done? (Hint: review the discussion on crispr)arrow_forward
- What is the major difference between genomic DNA and cDNA? List various vectors and state which is the best vector to create transgenic plants? What is the scientific logic on which CRISPR Technology has been designed? Why Artificial Intelligence is turning out to be a potential replacement for traditional radiological approaches? Review the introduction and discussion in the Nature Medicine Paper on the blackboard? What is immunotherapy? What was the underlying motivation that inspired James Allison to undertake this direction of research?arrow_forwardHow has the sequencing of human genome opened new window for treatment of various genetic disorders?arrow_forwardIn 1995, the first free-living organism to have its genome completely sequenced was Haemophilus influenzae, a bacteria. In the following year, the baker’s yeast Saccharomyces cerevisiae was the first eukaryote genome sequence to be fully sequenced. The complete sequencing of the human genome and related organisms represent one of the greatest scientific achievements in the history of mankind.Elaborate on the importance of genome studies in general.arrow_forward
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