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Chapter 4.10, Problem 24P

(a)

Interpretation Introduction

Interpretation:

From the given information, the configuration of naproxen should be determined.

Concept Introduction:

Enantiomeric excess:

The equal amount of isomers in the mixture is called racemic mixture and it have a 0 specific rotation so it is optically inactive value.

If a mixture contains unequal mixture of isomers means it can be optically active but the specific rotation value can varied by which enantiomer is present more than other isomer.

The excess of one isomer than other isomer in the mixture is known as enantiomeric excess (ee %), it is given by

ee%observed specific rotationspecific rotation of the pure enantiomer×100

(b)

Interpretation Introduction

Interpretation:

From the given information, the percentage of each isomer of Naproxen obtained from the commercial preparation should be determined.

Concept Introduction:

Enantiomeric excess:

The equal amount of isomers in the mixture is called racemic mixture and it have a 0 specific rotation so it is optically inactive value.

If a mixture contains unequal mixture of isomers means it can be optically active but the specific rotation value can varied by which enantiomer is present more than other isomer.

The excess of one isomer than other isomer in the mixture is known as enantiomeric excess (ee %), it is given by

ee%observed specific rotationspecific rotation of the pure enantiomer×100

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Chapter 4 Solutions

Organic Chemistry; Modified MasteringChemistry with Pearson eText -- ValuePack Access Card; Study Guide and Student Solutions Manual for Organic Chemistry, Books a la Carte Edition (7th Edition)

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