Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781260081848
Author: Robert Brooker
Publisher: Mcgraw-hill Higher Education (us)
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Chapter 41, Problem 2TY
Summary Introduction

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Hemorrhage is the loss of blood from a damaged blood vessel. It may decrease oxygen and nutrient delivery to the cells. Blood volume and blood pressure are closely related and directly proportional to each other. A decrease in volume due to hemorrhage can lead to a fall in the pressure as well.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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