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BIOLOGY:CONCEPTS+INVEST.-CONNECT ACCESS
5th Edition
ISBN: 9781260542233
Author: Hoefnagels
Publisher: MCG
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Question
Chapter 4.1, Problem 2MC
Summary Introduction
To determine:
The body possesses both potential and kinetic energy.
Concept introduction:
Energy is defined as the capacity to do work. Energy is conserved, that is, it can neither be created, nor be destroyed. It can only be transformed from one form to another. There are various types of energy, such as kinetic energy, electrical energy, chemical energy, thermal energy, potential energy, nuclear energy, and many more. The total amount of energy in a system is always constant.
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Students have asked these similar questions
Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug:
(a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate)
(b) Estimate the time for maximum plasma concentration (tmax).
(c) Estimate the maximum plasma concentration (Cmax).
(d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.)
(e)…
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Chapter 4 Solutions
BIOLOGY:CONCEPTS+INVEST.-CONNECT ACCESS
Ch. 4.1 - What are some examples of the work of a cell?Ch. 4.1 - Prob. 2MCCh. 4.1 - Prob. 3MCCh. 4.1 - Prob. 4MCCh. 4.2 - What is metabolism on a cellular level?Ch. 4.2 - Prob. 2MCCh. 4.2 - Prob. 3MCCh. 4.3 - What are the main parts of an ATP molecule?Ch. 4.3 - Prob. 2MCCh. 4.3 - Describe the relationships among endergonic...
Ch. 4.4 - Prob. 1MCCh. 4.4 - Prob. 2MCCh. 4.4 - Prob. 3MCCh. 4.4 - Prob. 4MCCh. 4.4 - List three conditions that influence enzyme...Ch. 4.5 - What is diffusion?Ch. 4.5 - What types of substances diffuse freely across a...Ch. 4.5 - Prob. 3MCCh. 4.5 - Prob. 4MCCh. 4.5 - Prob. 5MCCh. 4.5 - Prob. 6MCCh. 4.6 - How does a knifefish adjust its electric field?Ch. 4.6 - Prob. 2MCCh. 4 - Prob. 1MCQCh. 4 - Building proteins _____ energy; ATP hydrolysis...Ch. 4 - How does an enzyme affect the energy of a...Ch. 4 - Prob. 4MCQCh. 4 - Prob. 5MCQCh. 4 - Some people claim that lifes high degree of...Ch. 4 - List some examples of endergonic and exergonic...Ch. 4 - Why do electron transport chains release energy?Ch. 4 - Provide an example of an appliance that uses...Ch. 4 - Name at least four ways that a cell uses ATP.Ch. 4 - Use what you know about enzymes to propose an...Ch. 4 - Prob. 7WIOCh. 4 - Prob. 8WIOCh. 4 - Prob. 9WIOCh. 4 - Liver cells are packed with glucose. If the...Ch. 4 - Prob. 1PITCh. 4 - Prob. 2PITCh. 4 - Prob. 3PIT
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