EBK INQUIRY INTO LIFE: RELEVANCY UPDATE
15th Edition
ISBN: 9781260178012
Author: Mader
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 4.1, Problem 2LO
Describe the diverse roles of proteins in membranes.
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The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.
The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the
pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin.
You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?
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Chapter 4 Solutions
EBK INQUIRY INTO LIFE: RELEVANCY UPDATE
Ch. 4.1 - Describe the fluid-mosaic model of membrane...Ch. 4.1 - Describe the diverse roles of proteins in...Ch. 4.1 - Prob. 1QTCCh. 4.1 - Prob. 2QTCCh. 4.1 - Prob. 3QTCCh. 4.1 - Prob. 1CYPCh. 4.1 - Prob. 2CYPCh. 4.1 - In the fluid-mosaic model, the fluid properties...Ch. 4.1 - Prob. 2ACh. 4.1 - Prob. 3A
Ch. 4.2 - Prob. 1LOCh. 4.2 - Predict the movement of molecules in diffusion and...Ch. 4.2 - Prob. 3LOCh. 4.2 - Prob. 1CYPCh. 4.2 - Prob. 2CYPCh. 4.2 - Prob. 3CYPCh. 4.2 - Prob. 4CYPCh. 4.2 - Prob. 4ACh. 4.2 - Prob. 5ACh. 4.2 - Prob. 6ACh. 4.2 - Prob. 7ACh. 4.2 - Prob. 8ACh. 4.2 - Prob. 9ACh. 4.3 - Prob. 1LOCh. 4.3 - Prob. 2LOCh. 4.3 - Prob. 1CYPCh. 4.3 - Prob. 2CYPCh. 4.3 - Prob. 3CYPCh. 4.3 - Prob. 10ACh. 4.3 - Prob. 11ACh. 4 - Prob. S2.6BYBCh. 4 - Section 2.7 How does a protein’s shape relate to...Ch. 4 - Prob. F3.5BYBCh. 4 - Prob. 1CSCh. 4 - Prob. 2CSCh. 4 - Prob. 1TCCh. 4 - Prob. 2TC
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- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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