Chapter 4, Problem 63RE

Interpretation Introduction

Interpretation:

The “amyloid cascade hypothesis” is to be described.

Concept Introduction:

Alzheimer disease is a neurodegenerative disease, which starts slowly and gets worse with the passage of time. Alzheimer affected person suffer from memory loss, and in later stages it remove long-held memories. This disease is characterized by the presence of extracellular amyloid plaques and intracellular neurofibrillary tangles, resulting in neuronal dysfunction and cell death. Amyloid is characterized by general term for protein fragments that the body produces normally. Amyloid plaques are present between nerve cells (neurons) in the brain.