In 1919, Calvin Bridges began studying an X-linked recessive mutation causing eosin-colored eyes in Drosophila. Within an otherwise true-breeding culture of eosin-eyed flies, he noticed rare variants that had much lighter cream-colored eyes. By intercrossing these variants, he was able to make a true-breeding cream-eyed stock. Bridges now crossed males from this cream-eyed stock with true-breeding wild-type females. All the F progeny had red (wild-type) eyes. When F flies were intercrossed, the F progeny were 104 females with red eyes, 52 males with red eyes, 44 males with eosin eyes, and 14 males with cream eyes. Assume that these numbers represent an 8:4:3:1 ratio. Formulate a hypothesis to a. explain the F 1 and F 2 results, assigning phenotypes to all possible genotypes? What do you predict in the F 1 and F 2 generations if the parental cross is between true-breeding eosin eyed males and true-breeding cream eyed females? What do you predict in the F 1 and F 2 generations if the parental cross is between true-breeding eosin eyed females and true-breeding cream eyed males?

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Answer 1

Textbook Question

Chapter 4, Problem 33P

In 1919, Calvin Bridges began studying an X-linked recessive mutation causing eosin-colored eyes in Drosophila. Within an otherwise true-breeding culture of eosin-eyed flies, he noticed rare variants that had much lighter cream-colored eyes. By intercrossing these variants, he was able to make a true-breeding cream-eyed stock. Bridges now crossed males from this cream-eyed stock with true-breeding wild-type females. All the F progeny had red (wild-type) eyes. When F flies were intercrossed, the F progeny were 104 females with red eyes, 52 males with red eyes, 44 males with eosin eyes, and 14 males with cream eyes. Assume that these numbers represent an 8:4:3:1 ratio.

Formulate a hypothesis to a. explain the F₁ and F₂ results, assigning phenotypes to all possible genotypes?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed males
and true-breeding cream eyed females?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed females
and true-breeding cream eyed males?

Expert Solution

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

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Students have asked these similar questions

In Drosophila, a cross was made between females and wild-type males. The female parents expressed the three X-linked recessive traits miniature wing (m), ebony body (e) and cinnabar eye (c). In the F1, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F2 generation, and 1500 offspring were produced. 412 403 211 Miniature wing, ebony body, cinnabar eye Wild type Ebony body, cinnabar eye Miniature wing Miniature wing, cinnabar eye Ebony body Miniature wing, ebony body Cinnabar eye 224 103 96 23 28 (i) Using proper nomenclature, determine the genotypes of the females and males in generation P and F1. (ii) What is the correct order of the genes? (iii) Construct a genetic map showing the correct order and distances between these genes.

A Drosophila strain with two mutated phenotypes was crossed with a wild-type Drosophila strain. The wild-type phenotypes were present in all of the F1 flies. The F1 flies were bred with one another. The F2 generation, on the other hand, did not have the predicted 9:3:3:1 phenotypic ratio. Explain why these outcomes occurred.

Red eyes (r), brown color (b), and curled wings (c) are 3 recessive mutations that occur in house flies. These genes have already been mapped: r-b = 12 mu b-c = 18 mu r-c = 30 mu A fly with red eyes, brown color, and curled wings is crossed with a fly homozygous for the wild-type traits. The F1 males are crossed with females with the three mutant traits and 2000 progeny are produced. Find the number of observed double crossovers if the interference is 0.38. O 43 O 62 O 27 O 16

Answer 2

Textbook Question

Chapter 4, Problem 33P

In 1919, Calvin Bridges began studying an X-linked recessive mutation causing eosin-colored eyes in Drosophila. Within an otherwise true-breeding culture of eosin-eyed flies, he noticed rare variants that had much lighter cream-colored eyes. By intercrossing these variants, he was able to make a true-breeding cream-eyed stock. Bridges now crossed males from this cream-eyed stock with true-breeding wild-type females. All the F progeny had red (wild-type) eyes. When F flies were intercrossed, the F progeny were 104 females with red eyes, 52 males with red eyes, 44 males with eosin eyes, and 14 males with cream eyes. Assume that these numbers represent an 8:4:3:1 ratio.

Formulate a hypothesis to a. explain the F₁ and F₂ results, assigning phenotypes to all possible genotypes?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed males
and true-breeding cream eyed females?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed females
and true-breeding cream eyed males?

Expert Solution

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

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Answer 3

Textbook Question

Chapter 4, Problem 33P

In 1919, Calvin Bridges began studying an X-linked recessive mutation causing eosin-colored eyes in Drosophila. Within an otherwise true-breeding culture of eosin-eyed flies, he noticed rare variants that had much lighter cream-colored eyes. By intercrossing these variants, he was able to make a true-breeding cream-eyed stock. Bridges now crossed males from this cream-eyed stock with true-breeding wild-type females. All the F progeny had red (wild-type) eyes. When F flies were intercrossed, the F progeny were 104 females with red eyes, 52 males with red eyes, 44 males with eosin eyes, and 14 males with cream eyes. Assume that these numbers represent an 8:4:3:1 ratio.

Formulate a hypothesis to a. explain the F₁ and F₂ results, assigning phenotypes to all possible genotypes?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed males
and true-breeding cream eyed females?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed females
and true-breeding cream eyed males?

Expert Solution

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

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Answer 4

Textbook Question

Chapter 4, Problem 33P

In 1919, Calvin Bridges began studying an X-linked recessive mutation causing eosin-colored eyes in Drosophila. Within an otherwise true-breeding culture of eosin-eyed flies, he noticed rare variants that had much lighter cream-colored eyes. By intercrossing these variants, he was able to make a true-breeding cream-eyed stock. Bridges now crossed males from this cream-eyed stock with true-breeding wild-type females. All the F progeny had red (wild-type) eyes. When F flies were intercrossed, the F progeny were 104 females with red eyes, 52 males with red eyes, 44 males with eosin eyes, and 14 males with cream eyes. Assume that these numbers represent an 8:4:3:1 ratio.

Formulate a hypothesis to a. explain the F₁ and F₂ results, assigning phenotypes to all possible genotypes?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed males
and true-breeding cream eyed females?
What do you predict in the F₁ and F₂ generations if the parental cross is between true-breeding eosin eyed females
and true-breeding cream eyed males?

Expert Solution

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

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Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

Answer 8

Expert Solution

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Answer 9

Expert Solution

Answer 10

Expert Solution

Answer 11

Expert Solution

Answer 12

Summary Introduction

a.

To determine:

The hypothesis derived from the results obtained from crossing true breeding cream-colored male and true-breeding wild female.

Introduction:

Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.

Answer 13

Explanation of Solution

The hypothesis that can be derived from the results is that mutation in the wild type allele results in the production of eosin eyed progeny. The presence of criss-cross inheritance in the wild and the mutated variant results in the production of cream eyed progeny. This hypothesis supports the presence of criss-cross inheritance.

Answer 14

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Answer 15

Expert Solution

Answer 16

Expert Solution

Answer 17

Expert Solution

Answer 18

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed males and true-breeding cream-colored females.

Introduction:

The dominant allele masks the expression of the recessive allele. Therefore, the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.

Answer 19

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed males, and true-breeding cream-colored females are as follows:

Gametes	X^e	Y
X^c	X^eX^c	X^c Y
X^c	X^eX^c	X^c Y

The F₂ progeny is derived as follows:

Gametes	X^c	Y
X^e	X^eX^c	X^e Y
X^c	X^cX^c	X^c Y

The progeny obtained will be cream eyed males (X^c Y), eosin eyed males (X^e Y), cream-colored females (X^cX^c) and variant cream colored female (X^eX^c).

Answer 20

Expert Solution

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

Answer 21

Expert Solution

Answer 22

Expert Solution

Answer 23

Expert Solution

Answer 24

Summary Introduction

b.

To determine:

The predicted progeny in F₁ and F₂ generation if the cross is made between true-breeding eosin eyed females and true-breeding cream colored males.

Introduction:

The Punnett square is used to depict the genetic cross between two parents and all the possibilities of the resulting progeny that can help in identifying the genotype and phenotype of the hybrids produced.

Answer 25

Explanation of Solution

The progeny from the cross between true-breeding eosin eyed females, and true-breeding cream colored males are as follows:

Gametes	X^c	Y
X^e	X^cX^e	X^e Y
X^e	X^cX^e	X^e Y

The F2 progeny will be derived as follows:

Gametes	X^e	Y
X^e	X^eX^e	X^e Y
X^c	X^eX^c	X^c Y

The progeny obtained will have male genotype X^c Y, and X^e Y and females will have genotype X^eX^e and X^eX^c

Answer 26

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