FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
5th Edition
ISBN: 9781119750192
Author: Voet
Publisher: WILEY
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Question
Chapter 4, Problem 32CQ
Summary Introduction
To explain: Whether the modification of amino acid as shown in Fig.4.14 would affect the isoelectric point
Concept introduction: The peptide chains are generally modified for their specific purposes. The addition of a positively charged group or negatively charged group would affect the charge of the peptide chain and therefore it will affect the isoelectric point of the peptide.
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11. Which of the
compounds below is
the major product
of the following
reaction sequence?
NOTE: PCC is pyridinium chlorochromate
1. BH 3
PCC
2. H2O2, NaOH
NH
HN
ΗΝ,
A
B
C
CH3NH2, NaBH3CN
D
E
NH
10. Which of the compounds below is
the major organic product obtained
from the following reaction sequence?
Ph
Ph
Ph
A
B
OH
1. EtMgBr
H2CrO4
Zn(Hg), aq. HCI
PhCHO
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2. H₂O, H+
Ph.
C
D
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Chapter 4 Solutions
FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
Ch. 4 - Prob. 1ECh. 4 - 2. Glutamate, a 5-carbon amino acid, is the...Ch. 4 - Prob. 3ECh. 4 - Prob. 4ECh. 4 - 5. Draw the dipeptide Asp-His at pH 7.0.
Ch. 4 - 6. Calculate the number of possible pentapeptides...Ch. 4 - 7. Identify the hydrogen bond donor and acceptor...Ch. 4 - 8. In some proteins, the side chain of serine...Ch. 4 - 9. Determine the net charge of the predominant...Ch. 4 - 10. Determine the net charge of the predominant...
Ch. 4 - Prob. 11ECh. 4 - 12. Circle the chiral carbons in the following...Ch. 4 - Prob. 13ECh. 4 - 14. Patients with Parkinson’s disease are...Ch. 4 - 15. Over time, the glutamine residues of...Ch. 4 - 16. Some hormone-signaling pathways result in the...Ch. 4 - 17. Which amino acids have side chains that are...Ch. 4 - 18. Draw the structure of Lys and Ala linked by an...Ch. 4 - 19. Some bacteria produce poly-?-glutamic acid, a...Ch. 4 - Prob. 20ECh. 4 - 21. A sample of the amino acid tyrosine is barely...Ch. 4 - Prob. 22CQCh. 4 - 23. Calculate the pI of (a) Ala, (b) His, and (c)...Ch. 4 - Prob. 24CQCh. 4 - 25. Draw the peptide ATLDAK. (a) Calculate its...Ch. 4 - 26. The protein insulin consists of two...Ch. 4 - Prob. 27CQCh. 4 - 28. The two C?H atoms of Gly are said to be...Ch. 4 - Prob. 29CQCh. 4 - Prob. 30CQCh. 4 - 31. Identify the amino acid residue front which...Ch. 4 - Prob. 32CQCh. 4 - Prob. 33CQCh. 4 - Prob. 34CQCh. 4 - Prob. 1MTE
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