GENETIC ANALYSIS: AN INTEG. APP. W/MAS
GENETIC ANALYSIS: AN INTEG. APP. W/MAS
2nd Edition
ISBN: 9781323142790
Author: Sanders
Publisher: Pearson Custom Publishing
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Chapter 4, Problem 20P

Brachydactyly type D is a human autosomal dominant condition in which the thumbs are abnormally short and broad. In most cases, both thumbs are affected, but occasionally just one thumb is involved. The accompanying pedigree shows a family in which brachydactyly type D is segregating. Filled circles and squares represent females and males who have involvement of both thumbs. Halffilled symbols represent family members with just one thumb affected.

Chapter 4, Problem 20P, Brachydactyly type D is a human autosomal dominant condition in which the thumbs are abnormally

a. Is there any evidence of variable expressivity in this family? Explain.

b. Is there evidence of incomplete penetrance in this family? Explain.

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GENETIC ANALYSIS: AN INTEG. APP. W/MAS

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