Essentials of Biology
Essentials of Biology
4th Edition
ISBN: 9780078024221
Author: Sylvia S. Mader Dr., Michael Windelspecht
Publisher: McGraw-Hill Education
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Chapter 4, Problem 1TC
Summary Introduction

To determine:

a) The thought that a dietician might able to help a person with ALD.
b) The organelle which is similar in structure and function to a peroxisome.

Given:

The 1992 movie Lorenzo’s oils recount the story of six-year-old Lorenzo Odone and his battle with adrenoleukodystrophy (ALD) which is caused by a malfunctioning organelle called a peroxisome. A peroxisome is an organelle that ordinarily contains enzymes capable of breaking down long chain fatty acids. In ALD, the enzyme is missing, and when long-chain fatty acids accumulate, muscle weakness and loss of muscle control result.

Introduction:

The tiny, membrane-bound organelles that contain a variety of metabolic enzymes (nearly 50 enzymes) are the peroxisomes. Structurally they are analogous to lysosomes. By the process of replication, they are similar to mitochondria as well as chloroplasts, though they do not have the genome on their own. An X-linked disease may lead to the formation of long chain fatty acids, that leads to the destruction of the myelin sheath of the nerve fibers is the adrenoleukodystrophy (ALD).

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