Pathophysiology - E-Book
Pathophysiology - E-Book
6th Edition
ISBN: 9780323510424
Author: Banasik, Jacquelyn L.
Publisher: Saunders
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Chapter 4, Problem 1KQ
Summary Introduction

To determine: The usual cellular response to reversible injury.

Introduction: Damage to the cell is referred to as cellular injury. It is manifested as morphological and functional changes toward stress. Stress occurs due to internal and external environmental changes. The damage could be reversible or irreversible and it could be due to chemical, physical, and biological factors.

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The usual cellular responses to reversible injury are hydropic swelling and intracellular accumulation. These changes reflect the inability of the cells to perform the metabolic functions normally. This is because of the insufficient cellular energy in the form of ATP or due to the dysfunction of the metabolic enzymes.

The hydropic swelling occurs due to the pumping dysfunction of sodium and potassium ions at the membrane of the cell. Thus, the changes in ion concentration and water influx cause cellular swelling. Intracellular accumulation occurs due to abnormal exogenous and endogenous particles in the cell. This is an indication of a disorder of cellular metabolism.

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