Concept explainers
To determine: The sites in the body favorable for reproduction of poliomyelitis virus.
Introduction: The poliovirus causes poliomyelitis or polio or infantile paralysis. Poliovirus belongs to the family Picornaviridae and contains RNA as the genetic material. Polio was first described in 1789 and is also known as the leg wasting disease of children.
To determine: The possible outcome of infection of poliomyelitis virus.
Introduction: Poliovirus belongs to the family Picornaviridae and contains RNA as the genetic material. There are three different subtypes of poliovirus. The primary route of infection is the fecal-oral route. The virions are very stable and can remain infectious for long periods in food and water.

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Chapter 38 Solutions
CUSTOM PRESCOTT'S MICROBIOLOGY
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- What is the concept "calories consumed must equal calories burned" in regrads to nutrition?arrow_forwardYou intend to insert patched dominant negative DNA into the left half of the neural tube of a chick. 1) Which side of the neural tube would you put the positive electrode to ensure that the DNA ends up on the left side? 2) What would be the internal (within the embryo) control for this experiment? 3) How can you be sure that the electroporation method itself is not impacting the embryo? 4) What would you do to ensure that the electroporation is working? How can you tell?arrow_forwardDescribe a method to document the diffusion path and gradient of Sonic Hedgehog through the chicken embryo. If modifying the protein, what is one thing you have to consider in regards to maintaining the protein’s function?arrow_forward
- The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?arrow_forwardWhat protein is necessary for packaging acetylcholine into synaptic vesicles?arrow_forward
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