PRESCOTT'S MICROBILOGY
PRESCOTT'S MICROBILOGY
11th Edition
ISBN: 9781264075515
Author: WILLEY
Publisher: MCG
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Chapter 38.3, Problem 2CC
Summary Introduction

To determine: The reason for recurrent cold sores in people.

Introduction: Cold sore or a fever blister is a fluid-filled lesion that is commonly formed at the lips or the inside of nostrils. Cold sores present themselves near the nerve endings. As a result, they cause significant itching and burning sensation.

Summary Introduction

To determine: The causative agents of cold sores.

Introduction: Viruses consists of nucleic acid and a protein coat. Since viruses lack a cell division machinery, they are unable to replicate on their own. Hence, viruses multiply within the cells of the hosts by utilizing the host’s cell division machinery. Viruses are responsible for causing a range of diseases in humans.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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