To determine: The way by which ricin led to the death of Markov.
Introduction: Ricin is a highly toxic protein that is produced from Ricinus communis. The toxicity of ricin is not only twice to the cyanide, but also has the lethal effects much higher than the venom of a cobra. The compound is found to be present in the endosperm of the seed.

Explanation of Solution
Ricin is the combination of two compounds, ricin A and ricin B, in which ricin A is less toxic and found in the form of proricin. However, ricin B possesses the toxicity when disulfide bonds are hydrolyzed after the consumption of animals. The target site of ricin is the ribosome, which results in the inhibition of translation to form proteins.
Georgi Markov was a Bulgarian expatriate, who liked to do work as a novelist. On his way to London, a pinhead-sized metal from an umbrella pierced into the thigh of a person with intense pain. The metal contained approximately 0.2 mg of ricin compound, which injected into the skin of the person and caused the death of a person. The reason is that ricin led to stop the translation of protein and shutting down of
Want to see more full solutions like this?
Chapter 38 Solutions
BIOLOGY(LL)-W/ACCESS CODE >CUSTOM<
- Molecular Biology Question A gene that codes for a protein was removed from a eukaryotic cell and inserted into a prokaryotic cell. Although the gene was successfully transcribed and translated, it produced a different protein than it produced in the eukaryotic cell. What is the most likely explanation?arrow_forwardMolecular Biology LIST three characteristics of origins of replicationarrow_forwardMolecular Biology Question Please help. Thank you For E coli DNA polymerase III, give the structure and function of the b-clamp sub-complex. Describe how the structure of this sub-complex is important for it’s function.arrow_forward
- Molecular Biology LIST three characteristics of DNA Polymerasesarrow_forwardMolecular Biology RNA polymerase core enzyme structure contains what subunits? To form holo enzyme, sigma factor is added to core. What is the name of the structure formed? Give the detailed structure of sigma factor and the function of eachdomain. Please help. Thank youarrow_forwardMolecular Biology You have a single bacterial cell whose DNA is labelled with radioactiveC14. After 5 rounds of cell division, how may cells will contain radioactive DNA? Please help. Thank youarrow_forward
- 1. Explain the structure and properties of atoms and chemical bonds (especially how they relate to DNA and proteins). Also add some pictures.arrow_forward1. In the Sentinel Cell DNA integrity is preserved through nanoscopic helicase-coordinated repair, while lipids in the membrane are fortified to resist environmental mutagens. also provide pictures for this question.arrow_forwardExplain the structure and properties of atoms and chemical bonds (especially how they relate to DNA and proteins). Also add some pictures.arrow_forward
- In the Sentinel Cell DNA integrity is preserved through nanoscopic helicase-coordinated repair, while lipids in the membrane are fortified to resist environmental mutagens. also provide pictures for this question.arrow_forward1. Explain how genetic information is stored, copied, transferred, and expressed. Also add some pictures for this question.arrow_forward!. Describe biological macromolecules (DNA, RNA, proteins, lipids, etc.) and how they function in the cell. also provide some images for this question.arrow_forward
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningEssentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:CengageAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
- Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxCase Studies In Health Information ManagementBiologyISBN:9781337676908Author:SCHNERINGPublisher:Cengage


