Chapter 35, Problem 8TYU

Summary Introduction

To determine:

The feasibility of treating septic shock with the drug that blocks the TLR signaling using mutated mice that has mutation that cause the inactivation of the TLR gene and purified LPS.

Introduction:

TLR are the toll like receptors that are involved in the septic shock of the body that is induced by the lipopolysaccharides (LPS) of the gram negative bacteria when it is introduced into the blood. The TLR are the reason for the septic shock.