EBK ESSENTIALS OF PATHOPHYSIOLOGY
EBK ESSENTIALS OF PATHOPHYSIOLOGY
4th Edition
ISBN: 9781469893389
Author: PORTH
Publisher: WOLTERS KLUWER HEALTH (COURSE)
Question
Book Icon
Chapter 35, Problem 1RE

A.

Summary Introduction

To explain: The origin of pain stimuli in appendicitis and the associated neural pathway.

Introduction: Appendicitis refers to the medical condition characterized by the painful inflammation of the appendix leading to abdominal pain. The only way to treat this condition is the surgical removal of the appendix or appendicectomy.

A.

Expert Solution
Check Mark

Explanation of Solution

The pain in appendicitis begins around the umbilicus (belly button), which may come and go. This pain then spreads to the lower right abdomen turning out severe and constant.

The mechanism for this acute pain in the abdominal region is as follows:

The injury to the appendix leads to the release of inflammatory mediators such as prostaglandins, serotonin, and acetylcholine that causes inflammation. This stimulates the activation of nociceptors or pain receptors through which pain impulses are transmitted to the dorsal horn of the spinal cord. As the pain due to appendicitis is fast and sharply discriminated, it follows the neospinothalamic tract, which means that pain impulses are transmitted from the spinal cord to the thalamus for the interpretation.

B.

Summary Introduction

To explain: The neural mechanisms involved in the spasm of the overlying abdominal muscles.

Introduction: During appendicitis, the cramping in the abdominal region due to the rigid expansion of overlying muscles is referred to as abdominal spasm.

B.

Expert Solution
Check Mark

Explanation of Solution

Muscle spasm or guarding is a protective reflex rigidity. It acts as a protective mechanism as it minimizes the muscle movement and stabilizes the affected area. These spasms may result in mild, moderate, or severe pain in the lower region of the abdominal cavity.

C.

Summary Introduction

To explain: The significance of cool and moist skin along with the increased blood pressure, and heart rate during appendicitis.

Introduction: The blockage of the appendix often by feces or any foreign body may cause it to swell. This swelling is referred to as appendicitis, which may cause symptoms such as abdominal pain, loss of appetite, nausea, vomiting, severe cramps, and diarrhea.

C.

Expert Solution
Check Mark

Explanation of Solution

Other than abdominal pain, loss of appetite, nausea, and severe cramps, appendicitis also show symptoms such as cool and moist skin, increased blood pressure, and heart rate. The blockage of the appendix leads to increased blood pressure, while its rupture may cause an increased heart rate. This cardiogenic shock causes cool and clammy skin.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
None
Question #3: In the KeyGene paper, the authors state that it would be useful if pollen from an apomict would transmit apomixis-inducing genes to the female in the cross (assuming the pollen is viable). Assuming there was just one gene conferring gametophytic obligate apomixis, and that the two parents are inbreds, what would be the consequences of such a cross if: a) The apomixis was a dominant trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the parental cross. b) The apomixis was a recessive trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the…
Question #5: Assume that two genes are identified that confer gametophytic facultative apomixis in soybean. The genes show independent assortment. Recessive alleles at both loci are required for the facultative apomixis. Facultative apomixis is triggered when the temperature at pollination is above 20 degrees C. At temperatures below 20 degrees C, all reproduction is sexual, independent of genotype. A facultative apomict male, capable of producing viable pollen, was crossed with a sexually reproducing female. Assuming the parents are completely inbred, what are the predicted phenotypic ratios (apomict: non-apomict) for the F1, F2, and DH (F1-derived) generations at each of the following temperatures*: a) 15°C? b) 25°C? *for full credit, show crosses and genotypes where appropriate. Remember to position the female first (left side) in the cross. Type your answer here:
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Text book image
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Text book image
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Text book image
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education