The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified. Concept introduction: The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

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Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

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Fura-2 Fluorescence (Arbitrary Unit) 4500 4000 3500 3000 2500 2000 1500 1000 500 [Ca2+]=2970nM, 25°C [Ca2+] 2970nM, 4°C [Ca2+]=0.9nM, 25°C [Ca2+] = 0.9nM, 4°C 0 260 280 300 340 360 380 400 420 440 Wavelength (nm) ← < The figure on the LHS shows the excitation spectra of Fura-2 (Em = 510 nm) in 2 solutions with two different Ca2+ ion concentration as indicated. Except for temperature, the setting for excitation & signal acquisition was identical.< ப a) The unit in Y-axis is arbitrary (unspecified). Why? < < b) Compare & contrast the excitation wavelength of the Isosbestic Point of Fura-2 at 25 °C & 4 °C. Give a possible reason for the discrepancy. < c) The fluorescence intensity at 25 °C & 4 °C are different. Explain why with the concept of electronic configuration. <

Answer 2

Question

Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 4

Question

Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 5

Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Answer 6

Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Answer 7

Chapter 35, Problem 16P

Interpretation Introduction

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Answer 8

Expert Solution & Answer

Answer 9

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Answer 10

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Answer 11

Ch. 35 - Prob. 1P Ch. 35 - Prob. 2P Ch. 35 - Prob. 3P Ch. 35 - Prob. 4P Ch. 35 - Prob. 5P Ch. 35 - Prob. 6P Ch. 35 - Prob. 7P Ch. 35 - Prob. 8P Ch. 35 - Prob. 9P Ch. 35 - Prob. 10P

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified. Concept introduction: The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Solution Summary: The author explains that the peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Videos

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Want to see the full answer?

Chapter 35 Solutions

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified. Concept introduction: The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Solution Summary: The author explains that the peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Videos

Interpretation: The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified. Concept introduction: The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.

Want to see the full answer?

Chapter 35 Solutions

Interpretation:

The peptide sequence presented by the class-I MHC molecules to HLA-A2 should be identified.

Concept introduction:

The HLA is the human immunocyte antigen. They encode the MHC (major histocompatibility Complex) in humans. The MHC plays a major role in antigen representation.