INTEG. PRIN OF ZOO >LL< W/ CONNECT - FD
18th Edition
ISBN: 9781265230234
Author: HICKMAN
Publisher: MCG
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Question
Chapter 35, Problem 14RQ
Summary Introduction
To describe: The mechanism of immune system damage by HIV in AIDS patients.
Introduction: The immune system is a complex system that is essential for the survival of humans. The leukocytes or white blood cells are the immune cells that protect the body from foreign invaders. Lymphocytes are a class of leukocytes that include natural killer cells, T cells, and B cells.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 35 Solutions
INTEG. PRIN OF ZOO >LL< W/ CONNECT - FD
Ch. 35 - Distinguish susceptibility from resistance, and...Ch. 35 - Prob. 2RQCh. 35 - After a phagocyte has engulfed a particle, what...Ch. 35 - Prob. 4RQCh. 35 - What is the molecular basis of self and nonself...Ch. 35 - Prob. 6RQCh. 35 - Prob. 7RQCh. 35 - Prob. 8RQCh. 35 - Prob. 9RQCh. 35 - Prob. 10RQ
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