That how temporal summation of EPSPs from two presynaptic neurons results in a larger depolarization of the postsynaptic cell compared with how an inhibitory presynaptic neuron causes an IPSP that negates the EPSP of an excitatory neuron. And also explain how spatial summation of three excitatory presynaptic neurons produces an even larger depolarization of the postsynaptic neuron. Introduction: The postsynaptic neuron sums all the excitatory (EPSPs) and inhibitory (IPSPs) impulses that it receives. If the sum of this synaptic stimulation exceeds threshold, an action potential is generated which is passed on to the adjacent neuron. If the sum of synaptic inputs does not result in the exceeded threshold, an action potential will not be generated. EPSPs and IPSPs when summed over time, the firing up an action potential by the postsynaptic cell is determined by the frequency of synaptic stimuli. This summation is known as temporal summation. EPSPs and IPSPs when summed over space, the firing up an action potential is determined by the total number of synaptic stimuli received from various regions of the dendrites of the postsynaptic cell.

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Chapter 35, Problem 11SA

Summary Introduction

To describe:

That how temporal summation of EPSPs from two presynaptic neurons results in a larger depolarization of the postsynaptic cell compared with how an inhibitory presynaptic neuron causes an IPSP that negates the EPSP of an excitatory neuron. And also explain how spatial summation of three excitatory presynaptic neurons produces an even larger depolarization of the postsynaptic neuron.

Introduction:

The postsynaptic neuron sums all the excitatory (EPSPs) and inhibitory (IPSPs) impulses that it receives. If the sum of this synaptic stimulation exceeds threshold, an action potential is generated which is passed on to the adjacent neuron. If the sum of synaptic inputs does not result in the exceeded threshold, an action potential will not be generated.

EPSPs and IPSPs when summed over time, the firing up an action potential by the postsynaptic cell is determined by the frequency of synaptic stimuli. This summation is known as temporal summation.

EPSPs and IPSPs when summed over space, the firing up an action potential is determined by the total number of synaptic stimuli received from various regions of the dendrites of the postsynaptic cell.

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