The mucosal tolerance and role of gut microbiota in maintaining it. Introduction: The mucosal barriers are susceptible to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. The single layer of host colonocytes that lines the intestinal wall forms an impenetrable barrier that only pathogens can cross.

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Chapter 34.3, Problem 4CC

Summary Introduction

To describe: The mucosal tolerance and role of gut microbiota in maintaining it.

Introduction: The mucosal barriers are susceptible to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. The single layer of host colonocytes that lines the intestinal wall forms an impenetrable barrier that only pathogens can cross.

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